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Acyclovir 200mg
Medically Reviewed by – Alfie Thornton, PharmD
Last Updated on 26 June 2026

Acyclovir 200mg

$0.37 $0.45
Acyclovir 200mg tablets are prescription antiviral tablets used to treat herpes simplex infections, including cold sores and genital herpes, as directed by a doctor. Buy Acyclovir 200mg online in UK after a suitable consultation from a regulated pharmacy.
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Acyclovir 200mg CouponCoupon DescriptionCoupon Expiry Date
SUNNY28Summer Spectacular Sale2026-07-31
Categories: Anti ViralsTag: Pills

Quick Overview

Acyclovir 200mg is used for herpes simplex infections, including cold sores and genital herpes, and may be used for prevention in selected patients.
Key Detail Information
Product name Acyclovir 200mg Tablets
Active ingredient Aciclovir / Acyclovir
Medicine type Antiviral
Common use Herpes simplex infections, including cold sores and genital herpes
Prescription status Prescription-only medicine
Suitable for Adults and selected children when prescribed
Main safety point Dose adjustment may be needed in kidney problems

What is Acyclovir 200mg and used for?

Acyclovir 200mg is an antiviral tablet used to treat herpes simplex infections of the skin and mucous membranes. It may be prescribed for cold sores, genital herpes, recurrent herpes outbreaks, or prevention of herpes simplex infection in people at higher clinical risk. Acyclovir does not remove the herpes virus from the body. It helps reduce viral activity during treatment and may reduce symptom duration when taken correctly. It is most effective when started as soon as early symptoms appear, such as tingling, burning, itching, soreness, or small blisters.

How to take Acyclovir 200mg?

Acyclovir 200mg should be taken exactly as prescribed, with water, and spaced evenly across the day. For herpes simplex infections, it is commonly taken five times daily at about four-hour intervals, usually leaving out the night-time dose. You can take Acyclovir 200mg with or without food. If it upsets your stomach, taking it after food may help. Drink enough water during treatment, especially if you are older, taking repeated courses, or have kidney concerns. Do not take more tablets than prescribed. Do not stop early unless your doctor or pharmacist tells you to.

Benefits of Acyclovir 200mg

Acyclovir 200mg may help control herpes symptoms by reducing how quickly the virus multiplies in the body. When taken early, it may help reduce pain, soreness, blister formation, and healing time in suitable patients. Key benefits may include:
  • Helps treat herpes simplex infections
  • May reduce the severity of cold sores or genital herpes outbreaks
  • Can support faster symptom control when started early
  • May help prevent repeated herpes simplex infections in selected patients
  • Has a long history of clinical use when prescribed correctly
Acyclovir is not a guaranteed cure. Symptoms can return because herpes viruses can stay inactive in the body and reactivate later.

Who Can take Acyclovir 200mg?

Acyclovir 200mg may be suitable for adults and selected children who need antiviral treatment after clinical assessment. It should only be used when a doctor or prescribing pharmacist confirms it is suitable for your symptoms and medical history. Acyclovir 200mg may not be suitable if you:
  • Are allergic to acyclovir, aciclovir, valaciclovir, or any tablet ingredient
  • Have kidney disease or reduced kidney function
  • Are dehydrated or at risk of dehydration
  • Are elderly and more sensitive to kidney or nervous system side effects
  • Are pregnant, trying to conceive, or breastfeeding without medical advice
  • Have symptoms near the eye
  • Have a weakened immune system and severe or widespread infection
Get urgent medical help if you have eye pain, vision changes, confusion, severe headache, widespread rash, breathing difficulty, or swelling of the face, lips, tongue, or throat.

Dosage Information

Acyclovir 200mg dosage depends on the infection type, immune status, kidney function, age, and reason for treatment. Your prescriber will decide the right dose and course length for your condition. Common adult dosing patterns may include:
Use Common Prescribing Pattern
Herpes simplex infection 200mg five times daily, about four hours apart, usually for 5 days
Severe first infection Treatment may be extended if clinically needed
Prevention in immunocompromised patients 200mg four times daily, about six hours apart
Recurrent infection prevention Dose and duration depend on outbreak pattern and clinical risk
For shingles or chickenpox, aciclovir treatment usually needs higher doses than one 200mg tablet per dose. Do not use Acyclovir 200mg for a different condition unless prescribed.

How Long Does Acyclovir 200mg Take to Work?

Acyclovir 200mg starts working after absorption, but symptom improvement usually takes a few days of correct treatment. The medicine works best when started at the first sign of an outbreak, before blisters fully develop. Cold sores and genital herpes may feel less painful after a few days, but healing time varies. Complete the prescribed course even if symptoms improve early. Contact a healthcare professional if symptoms worsen, spread, or do not improve as expected.

Side effects of Acyclovir 200mg

Acyclovir 200mg can cause side effects, although many people tolerate it well at the prescribed dose. Common side effects may include headache, dizziness, feeling sick, vomiting, diarrhoea, stomach pain, tiredness, fever, itching, rash, or skin sensitivity to sunlight. Less common but serious side effects need urgent medical attention. These include:
  • Severe allergic reaction
  • Swelling of the face, lips, tongue, or throat
  • Breathing difficulty or wheezing
  • Confusion, hallucinations, tremors, seizures, or unusual drowsiness
  • Passing little or no urine
  • Kidney pain or lower back pain
  • Yellowing of the skin or eyes
  • Severe skin rash or blistering
Report suspected side effects to a doctor, pharmacist, or through the MHRA Yellow Card Scheme.

Warnings and Precautions

Acyclovir 200mg needs extra care in kidney disease, dehydration, older age, and weakened immune systems. Aciclovir is mainly removed from the body through the kidneys, so kidney function is important for safe dosing. Before taking Acyclovir 200mg, tell your prescriber if you:
  • Have kidney disease or reduced kidney function
  • Have ever had kidney problems with antiviral medicines
  • Are taking medicines that may affect the kidneys
  • Are pregnant or breastfeeding
  • Have a weakened immune system
  • Have frequent or severe herpes outbreaks
  • Have herpes symptoms affecting the eye
  • Are unable to drink enough fluids
For genital herpes, avoid sexual contact during an active outbreak. Condoms may reduce transmission risk between outbreaks, but they do not remove the risk completely.

Drug Interactions

Acyclovir 200mg can interact with medicines that affect kidney clearance or increase aciclovir levels in the blood. Always tell your doctor or pharmacist about prescription medicines, pharmacy medicines, and supplements you take. Important interactions may include:
Medicine Why it matters
Probenecid May increase aciclovir levels
Cimetidine May increase aciclovir exposure
Mycophenolate mofetil May increase levels of aciclovir-related substances
Theophylline Aciclovir may increase theophylline exposure
Ciclosporin or tacrolimus May increase kidney-related risk
Gentamicin or other aminoglycoside antibiotics May increase kidney strain
Regular high-dose NSAIDs such as ibuprofen or naproxen May increase kidney risk in some patients
This does not mean you must avoid all these medicines. It means your prescriber may need to check suitability, adjust treatment, or monitor you more closely.

Alternatives to Acyclovir 200mg

Alternatives to Acyclovir 200mg depend on the infection, severity, dosing preference, kidney function, and treatment aim. A clinician may suggest another antiviral if it is more suitable for your condition. Possible alternatives include:
  • Valaciclovir tablets
  • Famciclovir tablets
  • Acyclovir 400mg tablets
  • Acyclovir 800mg tablets
  • Aciclovir cold sore cream
  • Aciclovir eye ointment for herpes eye infection
Do not switch between antiviral medicines without medical advice. Doses and treatment schedules are different.

Lifestyle Advice for Anti Virals

Simple self-care steps can support antiviral treatment and reduce the chance of spreading herpes to others. These steps are especially important during active symptoms, when the virus is more likely to pass on. Helpful advice:
  • Start treatment as soon as early symptoms appear
  • Drink enough water while taking acyclovir
  • Wash your hands after touching affected skin
  • Do not pick blisters or scabs
  • Avoid kissing during cold sore symptoms
  • Avoid oral sex when you have a cold sore
  • Avoid sex during genital herpes symptoms
  • Keep affected skin clean and dry
  • Avoid sharing towels, lip balm, razors, or intimate items
  • Use sun protection if sunlight triggers cold sores
  • Rest if you feel unwell
Seek medical advice if symptoms are severe, keep returning, affect the eye, or do not improve.

FAQ's

What should I avoid when taking Acyclovir 200mg?

Avoid dehydration, missed doses, and close contact that may spread herpes during active symptoms. Drink enough water, take your tablets as prescribed, and avoid kissing, oral sex, or sexual contact while sores are present. Do not touch blisters and then touch your eyes, as herpes near the eye needs urgent medical care.

Can I drink alcohol with Acyclovir 200mg?

Alcohol is not known to directly stop Acyclovir 200mg from working. However, alcohol may worsen dizziness, sickness, dehydration, or tiredness in some people. If you feel unwell with a herpes outbreak or develop side effects, it is safer to avoid alcohol until you finish treatment and feel better.

How many days should you take Acyclovir 200mg?

Acyclovir 200mg is often taken for 5 days for herpes simplex infections, but your course may differ. Severe first infections may need longer treatment, while prevention plans can continue for a different duration. Follow the prescribed course exactly and speak to a pharmacist or doctor if symptoms continue.

Which organ does Acyclovir 200mg affect?

Acyclovir 200mg mainly involves the kidneys because the body removes aciclovir through urine. Most people take it safely, but kidney problems, dehydration, older age, or kidney-affecting medicines can increase side effect risk. Your dose may need adjustment if you have reduced kidney function.

Where can I buy Acyclovir 200mg online in UK?

You can buy Acyclovir 200mg online in UK only after a suitable prescription or regulated online consultation. Choose a UK-regulated pharmacy that checks your symptoms, medical history, allergies, pregnancy status, kidney health, and current medicines. Avoid websites selling prescription antivirals without checks, as this may be unsafe.

Medical Disclaimer

This page is for general medicine information only and does not replace advice from a doctor, pharmacist, or qualified healthcare professional. Always follow your prescription and read the patient leaflet supplied with your medicine. Read our medical disclaimer for more information.

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